Table 3.
Feature | Combined NIH/Belgian/Hamburg experience in pathologically proven glomus tumors |
Previously reported NF1- associated glomus tumors (pathologically-proven) |
Sporadic glomus tumors (data combined from van Geertruyden et al 1996 and Vasisht et al 2004) |
---|---|---|---|
Male:Female | 2 M (15%); 11 F (85%) | 2 M (29%); 5 F (71%) | 11 M (16%); 59 F (84%) |
Right:Left (Fingers and toes) | Right: 42%; Left: 58% | Right: 41%; Left: 59% | van Geertruyden: Right: 47%; Left: 53%; Vasisht: Right: 57%, Left: 42% |
Location of tumor | |||
Thumb (F1) | 1 (5%) | 2 (10%) | 17 (24%) |
F2 | 1 (5%) | 3 (14%) | 8 (11%) |
F3 | 6 (32%) | 5 (24%) | 18 (26%) |
F4 | 8 (42%) | 7 (33%) | 18 (26%) |
F5 | 3 (16%) | 4 (19%) | 9 (13%) |
Finger Totals | 19 (100%) | 21 (100%) | 70 (1005) |
Toes | 1 | 1 | 0 |
Patients with multi-focal tumors | 3/15 (20%) | 5/6 (83%) | None |
Years of symptoms prior to diagnosis | 1 to 40+ years | Up to 20 years | 1 to 40 years |
Average age of diagnosis (yrs) | 40 (combined, range 11–57); 54 (M, range: 50–57); 38 (F, range 11–57) | 33 (combined, range 17 – 53); 40 years (M, range: 35–45); 31 years (F, range: 17–53) | van Geertruyden: 44 (combined, range 26–83); Vasisht: 43 (combined, range: 14–95); 40 (M, range: 28–72); 43 (F, range: 14–95) |