Table I.
Biomarker | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | OR | 95% CI | P-value |
---|---|---|---|---|---|---|---|
CEA | 27.03 | 87.34 | 50.00 | 71.88 | 2.56 | 0.98–6.69 | 0.05600 |
CA19-9 | 21.62 | 92.41 | 57.14 | 71.57 | 3.36 | 1.11–10.06 | 0.03100 |
CA125 | 29.73 | 94.94 | 73.33 | 74.26 | 7.93 | 3.74–9.21 | 0.00050 |
Type IV collagen | 70.27 | 86.08 | 70.27 | 86.08 | 14.616 | 2.80–9.07 | <0.00001 |
PPV, positive predictive value; NPV, negative predictive value; OR, odds ratio; CI, confidence interval; CAE, carcinoembryonic antigen; CA, carbohydrate antigen.