Skip to main content
. 2012 May 29;20(8):1571–1581. doi: 10.1038/mt.2012.101

Figure 6.

Figure 6

Autonomous MyD88 signaling in B cells restores IgG2c. Curves represent the mean ± SEM of optical density for measuring anti-rAAV1 immunoglobulin G (IgG) levels at indicated serum dilutions in four independent experiments (n = 8–13 mice per group). IgG subtype in wild type (wt) mice (plain line) or MyD88−/− mice (large dotted line) or MyD88−/− mice restored with wt B cells (small dotted lines). Statistical analysis was performed on averaged area under the curve for sera of individual mice. rAAV1, recombinant adeno-associated virus serotype 1.