Figure 1.

Dietary D-glucarate effect on the serum level of interleukin (IL)-6 during the early post-initiation stages of benzo[a]pyrene (B[a]P)-induced lung tumorigenesis in A/J mice. The expression of proinflamatory IL-6 was significantly elevated in the B[a]P group at 2 weeks after the second dose of B[a]P. The decrease of IL-6 is also statistically significant in the remaining calcium D-glucarate (CG) CG groups. Statistical analysis was performed using the Student's t-test. Values are the means ± SD. The B[a]P group was compared to the control group and the CG groups were compared to the B[a]P group.