Figure 4.

Dietary D-glucarate effect on the serum level of interleukin (IL)-10 during the early post-initiation stages of benzo[a]pyrene (B[a]P)- induced lung tumorigenesis in A/J mice. The level of IL-10 was significantly elevated in the calcium D-glucarate (CG) groups at 4 weeks after the second dose of B[a]P, and significantly reduced in the CG groups at 6 weeks after the second dose of B[a]P. Student's t-test was used to compare the difference between the groups. Values are the means ± SD. The B[a]P group was compared to the control group and the CG groups were compared to the B[a]P group. The level of IL-10 was below detection at 10 weeks after the second dose of B[a]P.