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. Author manuscript; available in PMC: 2012 Aug 6.
Published in final edited form as: Recent Pat CNS Drug Discov. 2011 May 1;6(2):80–90. doi: 10.2174/157488911795933884

Fig. 1.

Fig. 1

Model shows the mechanism of release of activity dependent neurotrophic factor (ADNF) and activity dependent neuroprotective protein (ADNP). The release of vasoactive intestinal peptide (VIP) stimulates glial target receptor and induce vesicular excytosis contained ADNF and ADNP. ADNF and ADNP maintain neuronal survival in neurodegenerative diseases through unknown mechanism.