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Lytic transglycosylases cleave the N-acetylmuramic acid-β-1,4-N-acetylglucosamine bond in peptidoglycan (PG). The 1,6-anhydro PG monomers created by this reaction cause inflammation and cell death in several biological systems. The peptide chains of PG may have a terminal meso-DAP or D-Ala.
