Table 2.
Parameter | EST | SE | P | Parameter | EST | SE | P |
---|---|---|---|---|---|---|---|
TD Model | TU Model | ||||||
Treatment | −0.464 | 3.47 | 0.182 | Treatment | −1.144 | 1.18 | <0.001 |
Age | 0.023 | 0.15 | 0.124 | Age | −0.015 | 0.05 | 0.004 |
bECOG | −0.589 | 2.99 | 0.048 | bECOG | −0.805 | 1.74 | <0.001 |
Rectal | −0.028 | 3.20 | 0.929 | Rectal | −0.018 | 1.10 | 0.871 |
Male | −0.288 | 3.05 | 0.345 | Male | −0.054 | 1.09 | 0.622 |
CenEastEU | −0.188 | 6.27 | 0.764 | CenEastEU | 0.194 | 2.50 | 0.439 |
WesternEU | 0.181 | 3.99 | 0.650 | WesternEU | −0.068 | 1.60 | 0.672 |
TG Model | U Model | ||||||
Treatment | −0.784 | 2.14 | <0.001 | Intercept | 1.366 | 9.72 | 0.160 |
V*(1-Treatment) | −1.383 | 2.09 | <0.001 | Treatment | −1.070 | 3.19 | <0.001 |
Prog Time | −0.003 | 0.01 | 0.039 | Age | −0.008 | 0.14 | 0.546 |
PR Age | −0.004 | 0.05 | 0.450 | bECOG | 1.905 | 3.34 | <0.001 |
BTR PR | −0.226 | 3.45 | 0.512 | Rectal | 0.314 | 3.31 | 0.342 |
BTR SD | −0.180 | 1.74 | 0.302 | Male | −0.303 | 3.21 | 0.346 |
bECOG | −0.268 | 1.96 | 0.173 | CenEastEU | 0.078 | 6.23 | 0.901 |
LECOG | −1.035 | 1.48 | <0.001 | WesternEU | 0.346 | 4.12 | 0.400 |
AE | 0.295 | 1.16 | 0.011 |
EST, parameter estimates; SD(×10), standard error of the estimates; P, p-values; bECOG, baseline electrocorticography; CenEastEU, central Europe; WesternEU, western Europe; Prog Time, progression time; PR, partial response; BTR, best tumour response; SD, stable disease; LECOG, last electrocorticography; AE, adverse event.