Table 1. Downregulated genes detected by Affymetrix microarray.
| Gene names |
Average signals |
Fold change | P-value | |
|---|---|---|---|---|
| pLNCX2-B16 | CCR7-B16 | |||
| I. Interferon signaling and interferon responsive genes | ||||
| ifi203 (interferon activated gene 203) | 1393 | 13 | −107 | 3.668E-05 |
| Gbp2 (guanylate nucleotide binding protein 2) | 7236 | 70 | −106 | 6.2791E-06 |
| Iigp1 (interferon inducible GTPase 1) | 4373 | 43 | −101 | 3.7282E-06 |
| ifi47 (interferon gamma inducible protein 47) | 5471 | 73 | −74 | 3.3644E-05 |
| Igtp (interferon gamma induced GTPase) | 17576 | 307 | −57 | 2.6698E-05 |
| Iigp2 (interferon inducible GTPase 2) | 2598 | 53 | −49 | 1.8807E-05 |
| Irgm (interferon inducible protein 1) | 5838 | 265 | −22 | 2.2548E-05 |
| Ifit1 | 1506 | 86 | −17 | 4.774E-04 |
| STAT1 | 595 | 37 | −15 | 1.501E-04 |
| CCL5 | 1944 | 107 | −14 | 7.5336E-06 |
| IRF-1 (interferon regulatory factor 1) | 6130 | 645 | −9.5 | 2.316E-04 |
| IRF-7 (interferon regulatory factor 7) | 1144 | 136 | −8 | 1.0392E-03 |
| ifih1 | 848 | 120 | −7 | 1.7424E-05 |
| ifi35 (interferon-induced protein 35) | 7606 | 1440 | −5 | 1.3829E-05 |
| STAT2 | 435 | 93 | −4.7 | 2.0958E-03 |
| CXCL10 | 6536 | 2391 | −3 | 1.1254E-02 |
| II. MHC I and MHC II molecules | ||||
| H2-Ab1 | 2014 | 6 | −318 | 3.3439E-06 |
| CD74 (MHC II antigen-associated invariant polypeptide) | 24888 | 138 | −179 | 1.4918E-06 |
| H2-Eb1 | 5725 | 54 | −106 | 1.0800E-05 |
| H2-Mb1 | 2940 | 32 | −90 | 1.0802E-05 |
| H2-DMa | 2256 | 57 | −39 | 3.9023E-06 |
| H2-K1 | 6638 | 417 | −15 | 3.9538E-04 |
| B2m (beta-2-microglobulin) | 938 | 114 | −8 | 9.6454E-05 |
| III. Antigen presentation for MHC I | ||||
| Tap1 | 4005 | 140 | −28 | 2.4229E-05 |
| Tap2 | 1548 | 115 | −13 | 2.2663E-05 |
| Tapbp (tapasin) | 4475 | 666 | −6.7 | 1.1355E-05 |
Abbreviation: MHC, major histocompatibily complex. Fold-change: CCR7-B16/pLNCX2-B16.