Table 3.
Results of the Association Test forESR1Haplotypes between ASC and HBV-related ALF Groups
| Characteristic | AsC |
HBV-ALF |
P value | OR (95%CI) |
|---|---|---|---|---|
| (2n = 1714) | (2n = 690) | |||
| Haplotype, no. (%) | ||||
| [T; T] |
1023(59.7) |
365(50.8) |
|
|
| [T; C] |
142(8.3) |
82(11.5) |
|
|
| [C; T] |
54(3.1) |
36(5.0) |
|
|
| [C; C] |
495(28.9) |
235(32.7) |
|
|
| Total (3df) § |
|
|
0.0002 |
|
| Haplotype groups, no. (%) | ||||
| [T; T]/[T; T] |
294(34.3) |
97(27.1) |
|
|
| [T; T]/[-;-] |
435(50.8) |
171(47.6) |
|
|
| [-;-]/[-;-] | 128(14.9) | 91(25.3) | 0.0004 | 1.53(1.23 ~ 1.96) |
Notes: §For haplotype, P values were given by 2 × 4 table chi-square; ‘[-;-]’ means any other haplotypes; OR = odds ratio; CI = confidence interval; the association was analyzed by logistic regression analysis with adjustment for covariates, including age, sex, and alcohol consumption. AsC, asymptomatic carriers;HBV- ALF, patients with HBV-related acute liver failure.