Figure 2.

Pontine necrosis after SBRT. This patient was a 48-year-old male with type I NPC (a). He was treated with cisplatin-based concurrent chemoradiation via EBRT up to 59.4 Gy followed by CK-RS at 25 Gy in 5 fractions (b) and achieved CR in the response evaluation (c). Pontine necrosis developed 25.9 months after SBRT (d). He experienced various neurologic symptoms, including dizziness, gait disturbance, hoarseness, limb weakness, dysarthria and other cranial nerve signs and was still under rehabilitation and supportive care for debilitating symptoms at the time of analysis.