Table 5.
Dose-volume analysis of 4 major late complications
| Complications | OAR volume | EBRT dose | SBRT dose | EBRT D30% | EBRT D50% | SBRT Dmax at OAR | SBRT D10% | SBRT D30% | SBRT D50% | SBRT V50% | SBRT V70% |
|---|---|---|---|---|---|---|---|---|---|---|---|
| |
(cc) |
(Gy) |
(Gy/Fx) |
(Gy) |
(Gy) |
(Gy) |
(Gy) |
(Gy) |
(Gy) |
(%) |
(%) |
| Pontine necrosis (Brainstem) | |||||||||||
| 1 |
24.67 |
59.4 |
25/5 |
43.5 |
40.9 |
24.6 |
19 |
15.4 |
12.8 |
23.5 |
0.7 |
| 2 |
23.55 |
55.8 |
21/3 |
36.2 |
19.7 |
27.3 |
24.2 |
20.1 |
16.0 |
54.3 |
24.9 |
| Temporal lobe necrosis (Temporal lobe) | |||||||||||
| 1 |
63 |
45 |
25/5 |
48.1 |
45.3 |
28.4 |
17.9 |
10.3 |
6.2 |
11.2 |
4.4 |
| 2 |
66.02 |
70.2 |
21/3 |
37.4 |
11.7 |
25.0 |
16.5 |
8.9 |
4.9 |
18.8 |
5.7 |
| Optic retinopathy (Eyeball) | |||||||||||
| 1 |
10.7 |
45 |
25/5 |
45.1 |
45.1 |
27.7 |
23.7 |
18.4 |
13.3 |
35.9 |
12.8 |
| 2 |
11.2 |
50.4 |
20/5 |
52.1 |
49 |
22.5 |
21.1 |
18 |
13.5 |
50.6 |
25.9 |
| Optic neuropathy (Optic nerve) | |||||||||||
| 1 | 0.483 | 45 | 25/5 | 41.3 | 40.7 | 27.8 | 27.3 | 27.0 | 26.7 | 100 | 97.2 |
OAR, organ at risk; EBRT, external beam radiotherapy; SBRT, stereotactic body radiotherapy; Fx, fraction; Dx%, dose covering x% of total volume; Dmax, maximum dose; Vx%, volume receiving x% of prescribed dose.