Table 1. Assay Performance With Known HCV Inhibitors.

Inhibitor	Lifecycle stage/target	Luciferasea (EC50, nM)	Cellomicsa (EC50, nM)
EI	Entry/E2	33±6.3	31±9.5
BMS-339	Replication/NS3	256±25	270±22
BMS-052	Replication/NS5A	0.015±0.001	0.016±0.001
IDX184	Replication/NS5B	2,901±237	2,644±256
IFNα	Replication/host response	0.20±0.04b	0.17±0.08b
LY411575	Assembly/SPPc	10±3.3	11±4.1

^aAverage EC₅₀ (nM) ± standard deviation of at least three experiments.

^bInternational units per ml.

^cSPP, Signal peptide peptidase.