Table 1. Model parameters.
High | Middle | Low | Symbol | |||
Duration of maternal immunity (weeks) [21], [29] | 13 | 13 | 26 | 1/µ | ||
Life expectancy (years) | 80 | 75 | 60 | 1/d | ||
Duration of infectiousness (days) [23] | 7 | 7 | 7 | 1/γ | ||
Relative risk of infection following | ||||||
First infection | 0.62 | 0.62 | 0.61 | α 1 | ||
Second infection | 0.37 | 0.37 | 0.48 | α 2 | ||
Third infection | 0.37 | 0.37 | 0.33 | α 3 | ||
Proportion of infections with any GE (severe GE) | ||||||
First infection | 0.47 (0.28) | 0.47 (0.28) | 0.30 (0.17) | ξ 1 (φ 1) | ||
Second infection | 0.24 (0.19) | 0.24 (0.19) | 0.28 (0.23) | ξ 2 (φ 2) | ||
Third infection | 0.32 (0) | 0.32 (0) | 0.18 (0.24) | ξ 3 (φ 3) | ||
Fourth infection | 0.20 (0) | 0.20 (0) | 0.21 (0.18) | ξ 4 (φ 4) | ||
Source | [24] | [24] | [25] | |||
Proportion who seroconvert to vaccination [27] | 0.86 (0.67 to 0.98) | 0.74 (0.63 to 0.86) | 0.63 (0.58 to 0.67) | c | ||
Infectivity parameter* | Fitted | 0.235781 | 0.604687 | 2.25781 | q |
The infectivity parameter q represents the proportion of infectious contacts (i.e. when a susceptible and infectious individual come into contact) that result in transmission, multiplied by a constant factor by which the contact rate is assumed to scale across settings.