Table 3.

Neuropsychological features and cognitive domain scores for PD-MCI subtypes

	Amnestic Single- domain N=24	Amnestic Multiple- domain N=31	Nonamnestic Single- domain N=61	Nonamnestic Multiple- domain N=12	p value
MMSE	27.88 (1.92) *	26.39 (1.91)	27.87 (1.48) ^	25.08 (3.45)	<0.0001
Cognitive complaints, n (%)	18 (75)	31 (100)†	48 (78.7)	9 (75)	0.04
Hamilton Depression rating scale	5.61 (3.24)	7.61 (4.36)	7.39 (4.16)	7.33 (3.75)	0.26
UPDRS Thought disorder score (median, range)	0, 0–3	0.5, 0–4	0.5, 0–3	0.5, 0–1	0.84
Cognitive domain z-scores
Attentional/Executive Function	−0.70 (0.58)	−1.17 (0.57)	−0.82 (0.70)	−1.58 (0.50)	<0.0001
Memory	−1.95 (0.31)	−1.97 (0.40)	−0.60 (0.59)	−0.82 (0.54)	<0.0001
Language	0.89 (1.23)	0.25 (1.48)	0.55 (1.33)	−1.47 (2.44)	0.02
Visuospatial	−0.78 (0.71)	−2.95 (3.13)	−1.91 (1.66)	−2.77 (0.95)	<0.0001

Data presented as mean (SD), unless otherwise noted.

Abbreviations: MMSE, MiniMental State Examination; UPDRS, Unified Parkinson’s Disease Rating Scale.

^*Amnestic single-domain vs. Amnestic multiple-domain, p=0.03; vs. Nonamnestic multiple-domain, p<0.0001;

^{^}Nonamnestic single-domain vs. Amnestic multiple-domain, p=0.004; vs. Nonamnestic multiple-domain, p<0.0001;

^†Amnestic multiple-domain vs. Amnestic single-domain, p=0.02; vs. Nonamnestic single-domain, p=0.04; vs. Nonamnestic multiple-domain, p=0.02