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Amino acid sequence alignment of human WW1 and WW2_RW domains of WWOX with other WW domains within human proteome, identified through BLAST search, in which an arginine and a tryptophan are conserved at structurally-equivalent positions with respect to E66R and Y85W substitutions within WW2_RW mutant domain. Note that absolutely conserved residues within the WW domains are shown in red, semi-conserved residues in blue, and all other residues are colored black.
