Table 1.
Level 1 | Level 2 | |
Type 1 AIP | ||
Histology of the pancreas | LPSP (core biopsy/resection) | LPSP (core biopsy) |
At least 3 of the following: | Any 2 of the following: | |
(1) Periductal lymphoplasmacytic infiltrate without granulocytic infiltration | (1) Periductal lymphoplasmacytic infiltrate without granulocytic infiltration | |
(2) Obliterative phlebitis | (2) Obliterative phlebitis | |
(3) Storiform fibrosis | (3) Storiform fibrosis | |
(4) Abundant (> 10 cells/HPF) IgG4-positive cells | (4) Abundant (> 10 cells/HPF) IgG4-positive cells | |
Type 2 AIP | ||
Histology of the pancreas (core biopsy/resection) | IDCP | |
Both of the following: | Both of the following: | |
(1) GEL with or without granulocytic acinar inflammation (2) Absent or scant (0-10 cells/HPF) IgG4-positive cells | (1) Granulocytic and lymphoplasmacytic acinar infiltrate (2) Absent or scant (0-10 cells/HPF) IgG4-positive cells |
AIP: Autoimmune pancreatitis; LPSP: Lymphoplasmacytic sclerosign pancreatitis; IDCP: Idiopathic duct-centric pancreatitis; GEL: Granulocytic infiltration of the duct wall; IgG4: Immunoglobulin G4; HPF: High power field.