Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 Apr 24;40(14):6620–6631. doi: 10.1093/nar/gks327

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — Multiple sequence alignment of putative ALKBH2 and ALKBH3 proteins from plants and vertebrates. The alignment was generated with JalView (http://www.jalview.org/) using the embedded MUSCLE algorithm (55,56). The ‘Nucleotide Recognition Lid’ and the ‘Oxygenase Core’, described by Yu et al. (57), are indicated, as well as residues corresponding to Val101–Phe102 (involved in base flipping) and Arg-Lys–Lys (241–243) (involved in interaction with the opposite DNA strand) of human ALKBH2. The non-conserved N-terminal part of the proteins have been omitted from the alignment. Hs, Homo sapiens; Gg, Gallus gallus; Dr, Danio rerio; At, A. thaliana; Mt, Medicago truncatula (barrel medic); Vv, Vitis vinifera (common grape vine); Os, Oryza sativa (rice). GI numbers of sequences: 47124096 (Hs2), 118098574 (Gg2), 68383159 (Dr2), 18399917 (At2), 87162794 (Mt2), 147777784 (Vv2), 222635406 (Os2), 21040275 (Hs3), 118091513 (Gg3), 51011105 (Dr3).