Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2012 May 4;40(14):6898–6907. doi: 10.1093/nar/gks352

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2012. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Figure 1. — Updated consensus sequence and secondary structure model for OLE RNAs based on approximately 200 genomic and metagenomic representatives. Co-variation was calculated as described previously (19), and MI content of all possible nucleotide pairs was computed using published methods (5). P-values represent the probability of the given MI score occurring by chance in simulated neutral-evolution populations. A P-value cutoff of 10⁻⁴ is consistent with many base pairs predicted in previous models, and with two additional stems (P14a and P15). Potential tertiary interactions (Inset) are also evident. A P-value cutoff of 10⁻³ reveals possible base-pairing interactions (including P4a) that can form in at least 80% of the representatives (arrowhead).