Table 2.

Clinical and Pathologic Variables

Multivariatea (good vs poor clinical outcome)	Events	Correlation r	P value
Size vs survival	99	−0.23 (−0.41, −0.03)	.02
Portal tract vs survival	77	−0.33 (−0.51, −0.11)	.004
Ductal dysplasia vs portal tract	44	0.51 (0.25, 0.70)	.0004
Necrosis vs portal tract	38	0.56 (0.29, 0.74)	.003
Necrosis vs ductal dysplasia	38	0.48 (0.20, 0.70)	.002
Stromal infiltration vs ductal dysplasia	40	0.32 (0.01, 0.57)	.04
Perineural invasion vs recurrence	92	0.22 (0.02, 0.41)	.03
Perineural invasion vs size	89	−0.37 (−0.54, −0.18)	.0003
Perineural invasion vs portal tract	21	0.34 (0.13, 0.54)	.003
Perineural invasion vs ductal dysplasia	47	0.49 (0.24, 0.68)	.0005
Lymphatic vs survival	70	0.31 (0.08, 0.51)	.01
Lymphatic vs perineural invasion	61	0.42 (0.19, 0.61)	.0008
KRAS mutations vs perineural invasion	57	0.32 (0.06, 0.54)	.02

NOTE. Univariate analysis of survival and recurrence was tested by log-rank statistics.

^aThe correlation r is a partial correlation coefficient. Only statistically significant pairwise correlations are presented.