Table 3. Association between allelic variationa and CYP1A1 protein expression in pterygium (n=150) and controlb (n=50) subjects.
CYP1A1 protein expression, n (%) | |||
---|---|---|---|
Genotype | Negative | Positive | p |
Pterygium | 0.027 | ||
m1/m1 | 40 (39.2) | 10 (20.8) | |
m1/m2 and m2/m2 | 62 (60.8) | 38 (79.2) | |
Control | 1.000 | ||
m1/m1 | 25 (52.1) | 1 (50.0) | |
m1/m2 and m2/m2 | 23 (47.9) | 1 (50.0) |
aCYP1A1 allelic variants analyzed in this study are based on prior pterygium samples [14,15]. bFrom superior conjunctiva of 20 patients and medial conjunctiva of 30 patients without pterygium or pinguecula. The CIP 1A1 protein in pterygium and conjunctiva controls was detected by immunohistochemistry.