Table 3. Disribution of ACE I/D polymorphism and allele frequencies between AS patients and controls.
| Genotype | Patients (n=122; %) | Controls (n=140; %) | χ2 | p-value | OR (95%CI) |
|---|---|---|---|---|---|
| DD |
61 (50) |
29 (20.70) |
|
p<0.001 |
|
| II |
19 (15.57) |
68 (48.57) |
|
|
|
| ID |
42 (34.42) |
43 (30.70) |
|
|
|
| DD+ID:II |
103:19 |
72:68 |
32.00 |
p<0.001 |
5.087 (2.845–9.365) |
| ID+II:DD |
61:61 |
111:29 |
24.79 |
p<0.001 |
0.262 (0.1513–0.4495) |
| Allele frequency | |||||
| D |
164 (67.21) |
101 (36.07) |
21.64 |
p<0.001 |
2.426 (1.665–3.549) |
| I | 80 (32.79) | 179 (63.93) | |||
The results that are statistically significant are typed in bold.