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In vitro hexadecyloxypropyl cytarabine 3’,5’-cyclic monophosphate (HDP-cP-Ara-C) release profile. HDP-cP-Ara-C had a peak release around day 10, and the compound was still detectable at the end of the experiment (day 36). HDP-cP-Ara-C and hexadecyloxypropyl cytarabine 5’-monophosphate (HDP-P-Ara-C) were detected in the dissolution chamber eluate.
