Table 2. Aqueous level of erythropoietin (mIU/ml) in the control group, and glaucomatous eyes with controlled and uncontrolled intraocular pressure.
|
Eyes with controlled IOP (≤target pressure) |
Eyes with uncontrolled IOP (>target pressure) |
|
||||
---|---|---|---|---|---|---|---|
Groups | N | IOP (Mean±SD) | EPO (Mean±SE) | N | IOP (Mean±SD) | EPO (Mean±SE) | p-value** |
Control |
26 |
12.6±1.5 |
0.8±5.4 |
— |
— |
— |
— |
POAG |
27 |
14.1±3.6 |
14.8±6.3* |
13 |
28.7±6.5 |
20.4±6.3* |
0.147 |
PXFG |
15 |
14.5±3.7 |
4.7±1.5* |
11 |
31.5±12.2 |
28.2±13.9* |
0.256 |
NVG | 17 | 15.1±4.6 | 108.1±40.5* | 9 | 32.3±11.1 | 168.2±39.8* | 0.516 |
*Statistically significantly higher compared to the control group using Mann–Whitney U test (p<0.05); Target pressure: upper limit of intraocular pressure that prevents further glaucomatous damage; **Mann–Whitney U test was used for analysis, as the aqueous level of erythropoietin was not normally distributed. IOP: intraocular pressure; EPO: erythropoietin; POAG: primary open angle glaucoma; NVG: neovascular glaucoma; PXFG: pseudoexfoliative glaucoma.