Fig. 5.
Dorsal/ventral patterning of the pharyngeal arches requires Hh signaling. (A-F) 36 hpf embryos hybridized with probes for other markers of dorsal/ventral pattern in the pharyngeal arches. (A-D) In wild-type embryos, both (A) barx1 and (C) gsc have a dorsal and a ventral expression domain, with an intermediate domain free of expression (arrow). (B, D) In smo mutants, this intermediate region is lost (asterisk). (E & F) Expression of hand2 is similar between wild types and smo mutants (arrow). The first two arches are numbered. Anterior is to the left; dorsal is up in all images. Scale bar=50μm.