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Schematic description of the key nodal and internodal features of the mathematical model. Voltage-gated channels: sodium (transient (Na) and persistent (Nap)); potassium (fast (Kf) and slow (Ks)); HCN (H). Na+/K+-ATPase pump (Ipump). Ohmic leak conductance (Lk). Capacitance of: axolemma (internodal (Cax), nodal (Cn)); myelin sheath (Cm). Barrett–Barrett conductance (RB-B) through and under the myelin sheath.
