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. 2012 Aug 7;7(8):e42288. doi: 10.1371/journal.pone.0042288

Figure 10. Molecular modeling and docking of the hFcRn/m2a1/sp62 complex.

Figure 10

As predicted by modeling and docking, m2a1 interacts with sp62 by the loop FG, which is similar to the binding of 2F5 to sp62; and bind to FcRn by the residues around helix-1, which is consistent with the currently known FcRn binding site on the CH2 domain of Fc.