Table 3. Primers for limited mutagenesis of the m01s loop DE.
Position | Change to | Codon* | Comment | Diversity |
Y | hydrophobic amino acid | KHT | Unexpected “D” and “S” will be introduced | 6 |
N | neutral hydrophilic amino acid | WMC | An unexpected “Y” will be introduced | 4 |
S | neutral hydrophilic amino acid | WMC | An unexpected “Y” will be introduced | 4 |
T | neutral hydrophilic amino acid | WMC | An unexpected “Y” will be introduced | 4 |
Y | hydrophobic amino acid | KHT | Unexpected “D” and “S” will be introduced | 6 |
K = T + G, H = A + T + C, W = A + T, M = A + C.