Skip to main content
. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Neurogastroenterol Motil. 2011 Oct 11;23(12):1132–1139. doi: 10.1111/j.1365-2982.2011.01796.x

Figure 5.

Figure 5

Bifidobacterium longum fermented mediumdecreases the excitability of enteric neurons. (A) Representative image of an individual neuron being impaled with an intracellular microelectrode (in white). (B–D) Intracellular microelectrode recording showing action potentials discharged. Inset images show injection of a 500 ms duration current pulse with various intensities (pA). (B) Enteric neuron exposed to Krebs only. This neuron fired two action potentials in response to a supra-threshold current pulse set at threshold (350 pA) plus 50 millivolts. (C) Enteric neuron exposed to B. longum FM. No action potentials were discharged from this neuron after the injection of a 500 ms duration current pulse with 450 pA intensity. (D) Enteric neuron exposed to control (CM) only. This neuron fired one action potential in response to a supra-threshold pulse set at threshold plus 50 millivolts. (E) Electroresponsiveness of enteric nerves perfused with Krebs, CM or B. longum FM. Individual values are shown. Bars indicate mean (*P < 0.05 vs Krebs, #P < 0.05 vs CM).