Fig. 1.
IVIM simulations for tumor tissues using both Gaussian (solid line in red) and non-Gaussian (dot line in blue) diffusion model. Predicted signals (circle filled in red) at five b-values used in current study were depicted on the Gaussian diffusion model, from which a straight line (dash and dot in red) was fitted without b=0. The following parameters were used in the simulations (see Table 2): D = 1.0*10−3 mm2/s, D* = 25*10−3 mm2/s, f = 6% and K = 1.47 and 0 for non-Gaussian and Gaussian diffusion model, respectively.