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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Am J Geriatr Pharmacother. 2012 Jun 8;10(4):264–271. doi: 10.1016/j.amjopharm.2012.05.002

Table 1.

Increase in the Corrected QT Interval for Citalopram and Escitalopram*

Citalopram Dose ↑ in QTc Interval, msec (90% CI) Escitalopram Dose ↑ in QTc Interval, msec (90% CI)
20 mg/day 8.5 (6.2, 10.8) 10 mg/day 4.5 (2.5, 6.4)
40 mg/day 12.6 (10.9, 14.3) 20 mg/day 6.6 (5.3, 7.9)
60 mg/day 18.5 (16.0, 21.0) 30 mg/day 10.7 (8.7, 12.7)
Moxifloxacin 400 mg 13.4 (10.9, 15.9) Moxifloxacin 400 mg 9.0 (7.3, 10.8)

Abbreviations: CI, confidence interval; FDA, Food & Drug Administration

*

Adapted from references 6 and 7

Data extrapolated

P<0.05 compared to control