Table 1.
Citalopram Dose | ↑ in QTc Interval, msec (90% CI) | Escitalopram Dose | ↑ in QTc Interval, msec (90% CI) |
---|---|---|---|
20 mg/day | 8.5 (6.2, 10.8) | 10 mg/day | 4.5 (2.5, 6.4) |
40 mg/day† | 12.6 (10.9, 14.3) | 20 mg/day† | 6.6 (5.3, 7.9) |
60 mg/day | 18.5‡ (16.0, 21.0) | 30 mg/day | 10.7 (8.7, 12.7) |
Moxifloxacin 400 mg | 13.4 (10.9, 15.9) | Moxifloxacin 400 mg | 9.0 (7.3, 10.8) |
Abbreviations: CI, confidence interval; FDA, Food & Drug Administration
Adapted from references 6 and 7
Data extrapolated
P<0.05 compared to control