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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Transpl Immunol. 2012 Jun 5;27(1):52–54. doi: 10.1016/j.trim.2012.05.003

Figure 2.

Figure 2

Average OD values of anti-CD3 IT IgG antibody in monkeys without pre-existing antibody titers (Group 1; n=3) and monkeys with pre-existing antibody titers (Group 2; n=5) prior to and following anti-CD3 IT administration. We analyzed serum from 8 rhesus macaques for anti-CD3 IT antibody titers prior to and between 19-125 days following anti CD3-IT exposure. Group 1 animals (n=3) without pre-existing titers demonstrated an increase in titers and antibody concentration following exposure. Group 2 animals (n=5) with pre-existing titers did not show an overall increase titers or concentration.