Table 1.
Clinical and demographic characteristics of neonates.
| Group 1 (N=59) | Group 2 (N=35) | Group 3 (N=29) | P-value 1 vs. 2 | P-value 1 vs. 3 | |
|---|---|---|---|---|---|
| Sex of Child | |||||
| Male | 24 (40%) | 22 (63%) | 7 (24%) | 0.06 | 1.0 |
| Female | 34 (58%) | 13 (37%) | 10 (35%) | ||
| NA | 1 (2%) | 0 (0%) | 12 (41%) | ||
| Race/ethnicity | |||||
| White | 47 (80%) | 28 (80%) | 14 (48%) | 1.0 | 1.0 |
| Black | 3 (5%) | 2 (6%) | 0 (0%) | ||
| Hispanic | 2 (3%) | 0 (0%) | 4 (14%) | ||
| Asian | 5 (9%) | 3 (8%) | 0 (0%) | ||
| Other/NA | 2 (3%) | 2 (6%) | 11 (38%) | ||
| Antibody Status | |||||
| Anti-Ro52 | 58 (98%) | 35 (100%) | 27 (93%) | 1.0 | 0.3 |
| Anti-p200 | 50 (85%) | 33 (94%) | 21 (72%) | 0.2 | 0.2 |
| Anti-Ro60 | 59 (100%) | 35 (100%) | 29 (100%) | 1.0 | 1.0 |
| Anti-La | 30 (51%) | 23 (66%) | 17 (57%) | 0.2 | 0.5 |
| Gestational Age (wks) | 36.9 (±0.3)* | 37.9 (±0.3)† | 38.3 (±0.4)‡ | 0.004 | 0.005 |
| Birth weight (g) | 2746 (±104)§ | 3123 (±147)|| | 3078 (±181)¶ | 0.03 | 0.1 |
Group 1: cardiac NL, 3rd degree block (n=47), 2nd degree (n=2),1st degree (n=3), cardiomyopathy (n=5), sinus bradycardia (n=3)
Group 2: unaffectedwith at least one sibling with cardiac NL, cutaneous NL (n=4)
Group 3: unaffectedwith unaffected siblings, cutaneous NL (n=3), hepatic/hematological complications (n=1).
*
n=55,
†
n=35,
‡
n=15,
§
n=34,
||
n=18,
¶
n=9
NA=not available