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. Author manuscript; available in PMC: 2013 Aug 1.
Published in final edited form as: Am J Geriatr Pharmacother. 2012 Jun 9;10(4):230–241. doi: 10.1016/j.amjopharm.2012.05.001

Table 1.

Characteristics of Elder Caregivers and Dementia Patients, Overall and by Care-recipient Potentially Inappropriate Medication Use (n=566)

Study Variables Overall Sample Care-Recipient PIM Use (n=187) No Care-Recipient PIM Use (n=379) Difference: P-value
Predisposing characteristics
    Caregiver
        Age, mean (SD) 74.2 (6.0) 74.2 (6.1) 74.2 (6.0) 0.98
        Relationship to care-recipient, no. (%) 0.01
                Spouse 479 (84.6) 169 (90.4) 310 (81.8)
                Other relationship 87 (15.4) 18 (9.6) 69 (18.2)
        Education, no. (%) 0.65
                Less than high school degree 134 (23.7) 48 (25.7) 86 (22.7)
                High school degree only 150 (26.5) 46 (24.6) 104 (27.4)
                Some college 282 (49.8) 93 (49.7) 189 (49.9)
        Race/ethnicity, no. (%) 0.81
                White non-Hispanic 380 (67.1) 128 (68.5) 252 (66.5)
                Black non-Hispanic 96 (17.0) 29 (15.5) 67 (17.7)
                Hispanic 90 (15.8) 30 (16.0) 60 (15.8)
    Care-recipient
        Age, mean (SD), y 79.5 (6.6) 79.1 (6.2) 79.6 (6.8) 0.32
        Sex, no. (%) 0.59
                Male 345 (61.0) 111 (59.4) 234 (61.7)
                Female 221 (39.1) 76 (40.6) 145 (38.3)
Enabling characteristics
    Caregiver perceived financial inadequacy, mean (SD) 2.0 (1.0) 2.0 (1.0) 2.0 (1.0) 0.71
    Household Income, no. (%) 0.53
        <$20,000 222 (39.2) 68 (36.4) 154 (40.6)
        $20,00-39,999 218 (38.5) 73 (39.0) 145 (38.3)
        ≥ $40,000 126 (22.3) 46 (24.6) 80 (21.1)
    Caregiver employment status, no. (%) 0.32
        Works full or part-time 52 (9.2) 14 (7.5) 38 (10.0)
        Not working 514 (90.8) 173 (92.5) 341 (90.0)
    Years caregiver has lived in United States, mean (SD) 66.5 (16.6) 67.4 (16.6) 66.1 (16.6) 0.39
    Caregiver depressive symptoms (CES-D), mean (SD) 18.2 (11.1) 18.4 (10.8) 18.1 (11.3) 0.74
    Caregiver number of chronic conditions, mean (SD) 1.7 (1.2) 1.8 (1.2) 1.7 (1.2) 0.13
    Caregiver perceived health, no. (%)
        Perceived health is fair/poor 240 (42.4) 85 (45.6) 155 (40.9) 0.30
        Perceived health is good/very good/excellent 326 (57.6) 102 (54.6) 224 (59.1)
Need characteristics – Care-recipient
    Count of ADL and IADL limitations, mean (SD) 10.2 (3.1) 10.0 (3.2) 10.3 (3.0) 0.35
    Mini-mental State Examination, mean (SD) 12.9 (7.7) 13.9 (7.7) 12.4 (7.7) 0.03
    Revised Memory/Behavior checklist, mean (SD) 9.8 (3.8) 10.1 (3.8) 9.7 (3.8) 0.26
Medication Use in Past Month
    Care-recipient medication use
Total number of medications, mean (SD) 5.4 (3.3) 6.9 (3.4) 4.6 (3.0) <.001
Distribution of total medications, no. (%) <.001
                0-3 medications 178 (31.5) 27 (14.4) 151 (39.8)
                4-8 medications 295 (52.1) 106 (56.7) 189 (49.9)
                9 or more medications 93 (16.4) 54 (28.9) 39 (10.3)
        Care-recipient PIM use, no. (%) N/A
        No PIM 379 (67.0) N/A N/A
        ≥ 1 PIM 187 (33.0) N/A N/A
    Caregiver medication use
        Total number of medications, mean (SD) 4.4 (2.98) 5.1 (3.1) 4.0 (2.9) <.001
        Distribution of total medications, no. (%) <.001
                0-3 medications 243 (42.9) 62 (33.2) 181 (47.8)
                4-8 medications 271 (47.9) 99 (52.9) 172 (45.4)
                9 or more medications 52 (9.2) 26 (13.9) 26 (6.9)
    Caregiver PIM use, no. (%)
        No PIM 343 (60.6) 99 (52.9) 244 (64.4) 0.01
        ≥ 1 PIM 223 (39.4) 88 (47.1) 135 (35.6)

PIM, Potentially Inappropriate Medication ; SD, standard deviation; CG, Caregiver; ADL, Activities of Daily Living; IADL, Instrumental Activities of Daily Living; N/A, Not Applicable