TABLE 1.
More than 4-fold up-regulated genes by transient ZEB1 knockdown in ACC-MESO-1 cells
| Transient knockdown | Stable knockdown | Gene neame | |||
|---|---|---|---|---|---|
| Symbol | Fold | Log2 | Fold | Log2 | |
| EPCAM | 17.6 | 4.1 | 115.8 | 6.9 | Epithelial cell adhesion molecule |
| SPINT2 | 6.2 | 2.6 | 2.4 | 1.3 | serine peptidase inhibitor, Kunitz type, 2 |
| CDS1 | 6.1 | 2.6 | 5.1 | 2.4 | CDP-diacylglycerol synthase 1 |
| F2RL1 | 5.3 | 2.4 | 2.7 | 1.4 | coagulation factor II (thrombin) receptor-like 1 |
| DDIT4 | 5.3 | 2.4 | 4.6 | 2.2 | DNA-damage-inducible transcript 4 |
| IGSF6 | 5.3 | 2.4 | 0.1 | −2.9 | immunoglobulin superfamily, member 6 |
| PDE1C | 4.9 | 2.3 | 0.9 | −0.2 | phosphodiesterase 1C, calmodulin-dependent 70kDa |
| ARL15 | 4.7 | 2.2 | 0.3 | −2.0 | ADP-ribosylation factor-like 15 |
| TJP3 | 4.7 | 2.2 | 0.5 | −0.9 | tight junction protein 3 (zona occludens 3) |
| RNASEN | 4.7 | 2.2 | 0.0 | drosha, ribonuclease type III | |
| GRB14 | 4.5 | 2.2 | 7.4 | 2.9 | growth factor receptor-bound protein 14 |
| APOC2 | 4.4 | 2.1 | 0.7 | −0.5 | apolipoprotein C-II |
| SERPINI1 | 4.3 | 2.1 | 2.0 | 1.0 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| CLTCL1 | 4.3 | 2.1 | 1.3 | 0.4 | clathrin, heavy chain-like 1 |
| BCL7A | 4.1 | 2.0 | 1.0 | 0.0 | B-cell CLL/lymphoma 7A |
| AIF1L | 4.0 | 2.0 | 1.0 | 0.0 | allograft inflammatory factor 1-like |
| ADAMTS1 | 4.0 | 2.0 | 1.8 | 0.8 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 |