Table 1.

Parameters describing baroreflex control of sSNA after bilateral microinjection of orexin A (OX-A) (50 pmol)

	Lower plateau (%)	Upper plateau (%)	Mid point (mmHg)	Maximum gain (%/mmHg)	Range of SNA (%)	Threshold level (mmHg)	Saturation level (mmHg)	Operating range (mmHg)
Control	24.1 ± 6.9	93.2 ± 9.1	131.2 ± 3.2	−1.4 ± 0.2	57.3 ± 8.5	93.7 ± 6.5	168.8 ± 5.3	68.3 ± 10.2
OX-A (50 pmol)	26.5 ± 7.6 (ns)	131.0 ± 4.6**	138.0 ± 3.1 (ns)	−2.1 ± 0.3**	100.4 ± 5.2*	99.3 ± 3.6 (ns)	176.6 ± 7.5 (ns)	104.7 ± 16.2*

Values are mean ± SEM (n= 5). Maximum gain is the slope of the sigmoid curve of best fit at the MAP corresponding to steepest part of the curve.

^**P < 0.01,

^*P < 0.05 significantly different from control. ns, non-significant.