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. 2012 May 15;23(8):903–914. doi: 10.1089/hum.2012.015

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Copyright 2012, Mary Ann Liebert, Inc.

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FIG. 4. — Immunostaining with anti-ARSA (A) and anti-GFP (B) antibodies in the right internal capsule after a single injection of AAVrh.10cuARSA or AAVrh.10cuGFP vector into the right striatum. Cells having the morphology of oligodendrocytes and expressing ARSA (arrows in A) were 2-fold more abundant than cells having the morphology of oligodendrocytes and expressing GFP (arrows in B), suggesting a cross-correction of oligodendrocytes after injection of the AAVrh.10cuARSA vector. Nuclei are stained blue. Scale bars: 25 μm. Insets: Double immunostaining with CNPase (a marker for oligodendrocytes) and (A) ARSA or (B) GFP.