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. 2012 Sep;23(3):94–100. doi: 10.7171/jbt.12-2303-002
Q14. If the biosensor data do not fit a simple 1:1 binding model, what is the most important thing to do next?
Answer options Response percent Response count
Fit with a conformational change model. 8.6% 7
Fit with a heterogenous ligand or heterogenous analyte model. 9.9% 8
Reverse the immobilzation of analyte as ligand for the interaction. 21.0% 17
Verify the purity, homogeneity, and activity of my reagents. 46.9% 38
I don't fit biosensor data. 13.6% 11
answered question 81