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. 2012 Sep;23(3):94–100. doi: 10.7171/jbt.12-2303-002
Q20. How do you use change in enthalpy and change in heat-capacity data?
Answer options Response percent Response count
Use for quantitative, rational drug design 8.1% 6
Use to distinguish molecular binding mechanisms for different ligands or drugs 13.5% 10
Use to test if the binding model is a simple, noncooperative, single-binding site case or not 5.4% 4
Use as a strategy for measuring Kd at one temperature and then calculating Kd as a function of temperature 5.4% 4
No current need to use enthalpy change or heat capacity change 78.4% 58
answered question 74