Table 3.
The doses of two chemical diabetogenes in different species.
Chemicals | Species | Dose (s) in mg/kg |
---|---|---|
Alloxan | Rat | 40–200 (i.v./i.p.) |
Mice | 50–200 (i.v./i.p.) | |
Rabbit | 100–150 (i.v.) | |
Dog | 50–75 (i.v.) | |
| ||
Streptozotocin | Rat | 35–65 (i.v./i.p.) |
Mice | 100–200 (i.v./i.p.) | |
Hamster | 50 (i.p.) | |
Dog | 20–30 (i.v.) | |
Pig | 100–150 (i.v.) | |
Primates | 50–150 (i.v.) |
i.v.: intravenous; i.p.: intraperitoneal.
After [40].