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. 2012 Jul 12;7:3659–3666. doi: 10.2147/IJN.S33584

Figure 8.

Figure 8

Effect of HAP nanoparticles on the expression of caspase-3 and bcl-2 protein in U251 and SHG44 cells in vivo. (A) Representative images of western blotting analysis of caspase-3 and bcl-2 expression. (B and C) Level of the caspase-3 and bcl-2 protein expression in tumors.

Notes: Lane 1, the control group; lane 2, nano-HAP solution (25 mg/kg) group; lane 3, nano-HAP solution (50 mg/kg) group; lane 4, BCNU (25 mg/kg) group; lane 5, nano-HAP solution (25 mg/mL) and BCNU (25 mg/mL) group.

Abbreviations: Nano-HAP, hydroxyapatite nanoparticles; U251, human glioma U251 cells; SHG44, human glioma SHG44 cells; BCNU, 1,3-bis(2-chloroethyl)-1-nitrosourea.