Table S1.

Physicochemical characterization of permeation-enhanced dual drug-loaded nanoparticle preparations in different ratios of oleic acid concentration

Formulations	Size (nm)	PDI	Zeta potential (mV)
Without OA	477.4	0.509 ± 0.031	−31.4 ± 2.7
6.0 wt% OA	228.6	0.339 ± 0.023	−55.4 ± 3.9
5.5 wt% OA	120.8	0.305 ± 0.016	−53.3 ± 3.5
5.0 wt% OA	80.4	0.220 ± 0.021	−51.9 ± 2.3
4.5 wt% OA	41.3	0.118 ± 0.013	−47.3 ± 2.4
4.0 wt% OA	38.5	0.112 ± 0.023	−46.1 ± 1.9

Abbreviations: PDI, polydispersity index; OA, oleic acid.