Figure 6.

Cellular uptake (4 hours) of fluorescein-labeled small interfering RNA (siRNA) in MCF-7 and MDA-MB-231 human breast cancer cells after incubation with novel redox-responsive hyperbranched poly(amido amine) (named PCD)/siRNA binary complex and various siRNA/PCD/hyaluronic acid ternary complexes (siRNA/polycation/hyaluronic acid charge ratio of 1/20/16) prepared by different mixing orders.

Notes: The untreated cells were used as the control. *P < 0.01, significant difference between the two groups.