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. 2012 Jul 18;7:3823–3835. doi: 10.2147/IJN.S29328

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© 2012 Zou et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

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Particle sizes and zeta potentials of siRNA and DOX-loaded nanocomplexes (A) D-FPPP/Bcl-2 and (B) D-NPPP/Bcl-2 formed at different N/P ratios (n = 5), as determined by DLS measurements.

Note: DOX loading contents: 4.56% in D-FPPP and 5.14% in D-NPPP.

Abbreviations: DOX, doxorubicin; D-FPPP, DOX-loaded folate–poly(ethylene glycol)–poly(ethylene imine)–poly(ɛ-caprolactone) micelle; D-NPPP, DOX-loaded nontargeted poly(ethylene glycol)–poly(ethylene imine)–poly(ɛ-caprolactone) micelle; DLS, dynamic light scattering; D-FPPP/Bcl-2, Bcl-2 siRNA and DOX loaded folate–poly(ethylene glycol)–poly(ethylene imine)–poly(ɛ-caprolactone) micelle; D-NPPP/Bcl-2, Bcl-2 siRNA and DOX loaded nontargeted poly(ethylene glycol)– poly(ethylene imine)–poly(ɛ-caprolactone) micelle.