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. 2012 Sep;71(9):1510–1516. doi: 10.1136/annrheumdis-2011-200646

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Changes in adipocytokine serum levels after treatment with adalimumab. Serum levels of visfatin, resistin, vaspin, adiponectin and leptin from patients with RA were measured at baseline and after 16 weeks of treatment with adalimumab (40 mg subcutaneously every 2 weeks) in combination with methotrexate (stable dose for at least 16 weeks). Median (IQR) change (expressed as percentage) after treatment compared with baseline value is shown for all patients (A), EULAR good/moderate responders (B) and EULAR non-responders (C). Wilcoxon signed rank test was used to compare the changes for each adipocytokine. *p=0.004; **p=0.008; #p=0.004; ##p=0.002. EULAR, European League Against Rheumatism; RA, rheumatoid arthritis.