Figure 3. In vivo biocompatibility.
Implantation of low (A, B) or high (C, D) stiffness PGS scaffolds in a rat after induction of myocardial infarction by permanent ligation of the anterior descending coronary artery. Histological images show the integration between graft (stars) and the left ventricle (LV) at 2 weeks. Note the formation of blood vessels (arrow) in the higher magnifications view (B, D). Stain: Trichrome. Scale bars: 0.25 mm (A, C) and 0.1 mm (B, D).