Figure 1.

Intake of indomethacin results in minor intestinal cell damage and inflammation. (A) Plasma I-FABP levels increase after intake of indomethacin, indicating indomethacin-induced enterocyte damage. (B) Plasma calprotectin levels increase after intake of indomethacin, indicating inflammation after indomethacin ingestion.

Notes: Data are shown as the median (range) of baseline plasma samples (t = 0) of nine healthy individuals. *P < 0.05; **P < 0.01; ***P = 0.0005, significantly different from basal (placebo) conditions.

Abbreviations: PEG, polyethylene glycol; DS, dual sugar; I-FABP, intestinal fatty acid binding protein.