Table 3.

Overall accuracy and cutoff points of both urine-based permeability tests

Urinary collection	Cutoff point (μmol)	Sensitivity	Specificity	AUC (95% CI)	P
PEG 400
0–1-h	2288	89%	67%	0.79 (0.57–1.01)	<0.05
1–2-h	1507	100%	67%	0.85 (0.67–1.03)	0.01
0–2-h	5226	89%	78%	0.84 (0.65–1.03)	<0.05
0–5-h	7251	89%	78%	0.83 (0.63–1.03)	<0.05
PEG 1500
0–1-h	5.00	100%	56%	0.74 (0.49–0.99)	0.09
1–2-h	9.00	100%	67%	0.79 (0.56–1.01)	<0.05
0–2-h	20.00	100%	56%	0.77 (0.53–1.01)	0.06
0–5-h	33.00	100%	67%	0.74 (0.48–1.00)	0.09
PEG 3350
0–1-h	0.05	78%	56%	0.64 (0.38–0.90)	0.31
1–2-h	0.15	78%	78%	0.77 (0.53–1.00)	0.06
0–2-h	0.15	89%	56%	0.74 (0.50–0.98)	0.09
0–5-h	0.75	89%	78%	0.78 (0.54–1.02)	<0.05
PEG 3350/400
0–1-h	5e–005	67%	89%	0.77 (0.54–1.00)	0.05
1–2-h	5e–005	78%	89%	0.79 (0.55–1.03)	<0.05
0–2-h	5e–005	78%	89%	0.80 (0.58–1.03)	<0.05
0–5-h	5e–005	89%	89%	0.85 (0.66–1.06)	0.01
L/R ratio
0–1-h	0.17	75%	100%	0.85 (0.62–1.09)	<0.05
1–2-h	0.105	78%	89%	0.86 (0.68–1.04)	<0.05
0–2-h	0.13	78%	100%	0.87 (0.69–1.07)	<0.05
0–5-h	0.18	78%	78%	0.77 (0.65–1.08)	0.08

Abbreviations: AUC, area under the curve; CI, confidence interval; PEG, polyethylene glycol; h, hour.