Table 1. Genes with at least one CpG site differentially methylated in early pregnancy compared with both non–pregnancy groups (nulligravid and postpartum) that were significant at the 10% FDR level (q < 0.10).
| Gene Symbol |
Mean methylation Nulligravid |
q value (Nulligravid vs. Pregnant) |
Mean Methylation Pregnant |
q value (Postpartum vs. Pregnant) |
Mean Methylation Postpartum |
|---|---|---|---|---|---|
|
TREML1 |
0.213 |
0.086 |
0.166 |
0.011 |
0.213 |
|
NDUFS2 |
0.338 |
0.086 |
0.267 |
0.025 |
0.333 |
|
IL1R2 |
0.251 |
0.086 |
0.185 |
0.044 |
0.250 |
|
PTPRJ |
0.396 |
0.086 |
0.323 |
0.053 |
0.380 |
|
SPAG4 |
0.551 |
0.086 |
0.464 |
0.011 |
0.557 |
|
HPR |
0.459 |
0.086 |
0.387 |
0.032 |
0.458 |
|
CCIN |
0.401 |
0.089 |
0.285 |
0.044 |
0.389 |
|
PC |
0.584 |
0.097 |
0.514 |
0.092 |
0.578 |
| CTGLF1 | 0.824 | 0.098 | 0.788 | 0.025 | 0.824 |