Table 1. Top 10 molecules showing similar expression patterns of transcriptional response modules to letrozole.
FOXM1 transcription factor network | IGF1 pathway | IL4-mediated signaling events | LPA receptor mediated events | Plasma membrane estrogen receptor signaling | Reelin signaling pathway | Stabilization and expansion of the E-cadherin adherens junction | |
Fulvestrant | O | O | O | O | O | O | |
Trichostatin A | O | O | O | O | O | ||
Irinotecan | O | O | O | O | O | ||
Ag-013608 | O | O | O | ||||
Tretinoin | O | O | O | ||||
Metamizole sodium | O | O | O | ||||
Tanespimycin | O | O | O | ||||
Vorinostat | O | O | O | ||||
Verteporfin | O | O | |||||
Daunorubicin | O | O |